SCHEMBL3131808

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15946004	0.90	MAPT (0.48)	ALDH1A1MAPTPRMT5WDR77HDAC11
	SCHEMBL2150900	0.84	HDAC11 (0.49)	ALDH1A1MAPTCA12CA1CA2
	SCHEMBL2151021	0.84	CA12 (0.46)	ALDH1A1MAPTCA12CA1CA2
	SCHEMBL13033166	0.83	ALDH1A1 (0.55)	ALDH1A1MAPTMTNR1AMTNR1B
	SCHEMBL3127740	0.82	FFAR1 (0.45)	CA12CA1CA2CA9HTR7
	SCHEMBL3127758	0.81	POLB (0.42)	ALDH1A1MAPTCA1CA2THRA
	SCHEMBL2151036	0.77	NPC1 (0.51)	ALDH1A1MAPTCA12CA1CA2
	SCHEMBL11935029	0.76	NPSR1 (0.49)	HDAC11HDAC8MTNR1AMTNR1B
	SCHEMBL15945985	0.76	HDAC11 (0.51)	ALDH1A1MAPTCA12CA1CA2
	SCHEMBL11935015	0.76	SMN1; SMN2 (0.49)	ALDH1A1MAPTMTNR1AMTNR1BTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.