Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13033122 | 0.85 | TRPV1 (0.44) | ALDH1A1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL3131808 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MTNR1AMTNR1BMAPT | |
| SCHEMBL15946004 | 0.83 | MAPT (0.48) | ALDH1A1RAB9AHPGDLMNAGAA | |
| SCHEMBL11115690 | 0.82 | KMT2A (0.61) | ALDH1A1RAB9ANPC1HPGDLMNA | |
| SCHEMBL11108977 | 0.82 | KMT2A (0.53) | ALDH1A1RAB9ANPC1HPGDLMNA | |
| SCHEMBL13033087 | 0.82 | SCN5A (0.53) | ALDH1A1RAB9ALMNAMAPK1L3MBTL1 | |
| SCHEMBL9816317 | 0.81 | L3MBTL1 (0.55) | ALDH1A1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL11935015 | 0.81 | SMN1; SMN2 (0.49) | ALDH1A1RAB9ANPC1HPGDLMNA | |
| SCHEMBL30027786 | 0.81 | ALDH1A1 (0.64) | ALDH1A1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL11113486 | 0.81 | KMT2A (0.51) | ALDH1A1RAB9ANPC1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286035-A1 | NEUROMEDIN U DERIVATIVE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286035-A1 | NEUROMEDIN U DERIVATIVE | NMUR1, NMUR2, NMBR | ALDH1A1 3894/4885RAB9A 3497/4885NPC1 3579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.