Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 8/20 | 0.54 |
| ▸ | EGFR | P00533 | 10/20 | 0.52 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.49 |
| ▸ | NUAK2 | Q9H093 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318206 | 0.88 | MAP3K7 (0.47) | ALKEGFRMAP3K7 | |
| SCHEMBL29097720 | 0.87 | EGFR (0.51) | ALKEGFRMAP3K7JAK3NUAK1 | |
| SCHEMBL29097557 | 0.84 | EGFR (0.54) | ALKEGFR | |
| SCHEMBL30621968 | 0.84 | EGFR (0.59) | ALKEGFRMAP3K7 | |
| SCHEMBL29097707 | 0.84 | EGFR (0.59) | ALKEGFRMAP3K7 | |
| SCHEMBL29097555 | 0.84 | EGFR (0.54) | ALKEGFRMAP3K7JAK3 | |
| SCHEMBL12628011 | 0.78 | ALK (0.71) | ALKEGFR | |
| SCHEMBL31318205 | 0.75 | STK17B (0.46) | — | |
| SCHEMBL29097572 | 0.74 | MAP3K7 (0.47) | ALKEGFRMAP3K7JAK3 | |
| SCHEMBL29097552 | 0.72 | EGFR (0.57) | ALKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011447-A1 | PYRIMIDINAMINE NUAK INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 特科罗生物科技(成都)有限公司 | 2025-01-16 | — | — | WO | disclosed |