Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.46 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.38 |
| ▸ | RET | P07949 | 6/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318206 | 0.79 | MAP3K7 (0.47) | — | |
| SCHEMBL30621963 | 0.78 | DPP4 (0.32) | DRD2MCHR1 | |
| SCHEMBL29097568 | 0.78 | DPP4 (0.32) | DRD2MCHR1 | |
| SCHEMBL31318199 | 0.75 | ALK (0.54) | — | |
| SCHEMBL1997960 | 0.75 | NPFFR1 (0.58) | DRD2NPFFR1NPFFR2MCHR1 | |
| SCHEMBL29097567 | 0.75 | PDCD1 (0.33) | STK17BSTK17APDCD1CD274FLT4 | |
| SCHEMBL29097706 | 0.74 | SCN9A (0.34) | — | |
| SCHEMBL30621970 | 0.74 | SCN9A (0.34) | — | |
| SCHEMBL30621964 | 0.73 | PTPN11 (0.39) | PDCD1CD274 | |
| SCHEMBL29097722 | 0.73 | PTPN11 (0.39) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011447-A1 | PYRIMIDINAMINE NUAK INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 特科罗生物科技(成都)有限公司 | 2025-01-16 | — | — | WO | disclosed |