Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 3/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.31 |
| ▸ | PARG | Q86W56 | 3/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30621970 | 1.00 | SCN9A (0.34) | SCN9ASCN4ASCN5ASMOSCN1A | |
| SCHEMBL29097714 | 0.81 | ABL1 (0.39) | SMOPARGBRD4 | |
| SCHEMBL30621965 | 0.81 | ABL1 (0.39) | SMOPARGBRD4 | |
| SCHEMBL29097550 | 0.79 | BRD4 (0.56) | BRD4 | |
| SCHEMBL29097722 | 0.75 | PTPN11 (0.39) | — | |
| SCHEMBL30621964 | 0.75 | PTPN11 (0.39) | — | |
| SCHEMBL31318205 | 0.74 | STK17B (0.46) | — | |
| SCHEMBL30621963 | 0.74 | DPP4 (0.32) | — | |
| SCHEMBL29097568 | 0.74 | DPP4 (0.32) | — | |
| SCHEMBL30621975 | 0.72 | TRPV1 (0.41) | SMOPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903592-A | Pyrimidine amine NUAK inhibitor and preparation method and application thereof | 特科罗生物科技(成都)有限公司 | 2023-10-20 | — | — | CN | disclosed |