Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128689 | 0.95 | PDE4A (0.48) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3121033 | 0.82 | ALDH1A1 (0.42) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3120367 | 0.82 | L3MBTL1 (0.39) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3126032 | 0.82 | PDE4A (0.46) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3132672 | 0.82 | PDE4B (0.45) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3131094 | 0.81 | PDE4A (0.47) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3131223 | 0.81 | L3MBTL1 (0.40) | — | |
| SCHEMBL3121296 | 0.80 | L3MBTL1 (0.39) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL3117583 | 0.80 | MAPT (0.44) | — | |
| SCHEMBL3133274 | 0.77 | PDE4A (0.54) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |