SCHEMBL31318484

SCHEMBL31318484

c1coc(-c2ccc3[nH]c4ccc(-c5ccco5)cc4c3c2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.55
GABRG2 P18507 2/20 0.55
GABRB3 P28472 2/20 0.55
GABRA5 P31644 2/20 0.55
GABRA3 P34903 2/20 0.55
GABRA2 P47869 2/20 0.55
GABRA6 Q16445 2/20 0.55
GABRA4 P48169 1/20 0.52
TAAR1 Q96RJ0 2/20 0.47
CTSV O60911 1/20 0.46
CTSL P07711 1/20 0.46
TUBB4A P04350 1/20 0.44
TUBB P07437 1/20 0.44
TUBA3C P0DPH7 1/20 0.44
TUBA1B P68363 1/20 0.44
TUBA4A P68366 1/20 0.44
TUBB4B P68371 1/20 0.44
TUBB3 Q13509 1/20 0.44
TUBB2A Q13885 1/20 0.44
TUBB8 Q3ZCM7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29503092 0.93 CTSV (0.53) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL5219753 0.82 CA12 (0.46) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL676127 0.81 GABRA1 (0.45) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL675231 0.80 GABRA1 (0.44) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL676503 0.80 GABRA1 (0.49) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL3671654 0.77 CCNB2 (0.46) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL676261 0.76 ALK (0.52) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL1180049 0.76 JAK2 (0.59) TAAR1PIM1
SCHEMBL13615852 0.76 TAAR1 (0.50) TAAR1GPR17ERN1PGRKEAP1
SCHEMBL394300 0.73 TAAR1 (0.76) TAAR1ERN1PGRKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285635-A Synthesis of 8H-indolo [3,2,1-DE ] phenanthridine-8-ketone compound from carbazole and o-bromobenzoic acid and synthesis method thereof 陕西科技大学 2025-01-10 CN claimed
CN-119285635-A Synthesis of 8H-indolo [3,2,1-DE ] phenanthridine-8-ketone compound from carbazole and o-bromobenzoic acid and synthesis method thereof 陕西科技大学 2025-01-10 CN disclosed