Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318513 | 0.87 | MEN1 (0.42) | KMT2AMEN1GPR35SLC22A12CYP2C9 | |
| SCHEMBL31318564 | 0.87 | ALDH1A1 (0.35) | KMT2AMEN1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL31318532 | 0.84 | SLC22A12 (0.42) | KMT2AMEN1GPR35SLC22A12CYP2C9 | |
| SCHEMBL31318498 | 0.83 | SLC22A12 (0.44) | TTRKMT2AMEN1GPR35SLC22A12 | |
| SCHEMBL31318492 | 0.79 | MEN1 (0.40) | KMT2AMEN1GPR35SLC22A12CYP2C9 | |
| SCHEMBL31318547 | 0.76 | SLC22A12 (0.39) | SLC22A12CYP2C9ABCG2MAPTTP53 | |
| SCHEMBL31318539 | 0.75 | SLC22A12 (0.50) | SLC22A12CYP2C9ABCG2 | |
| SCHEMBL31318548 | 0.75 | ALDH1A1 (0.40) | KMT2AMEN1SLC22A12ALDH1A1L3MBTL1 | |
| SCHEMBL31318515 | 0.72 | SLC22A12 (0.44) | SLC22A12CYP2C9ABCG2 | |
| SCHEMBL31318506 | 0.72 | SLC22A12 (0.48) | SLC22A12CYP2C9ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |