Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.30 |
| ▸ | PGR | P06401 | 2/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.30 |
| ▸ | AR | P10275 | 2/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.30 |
| ▸ | HTR6 | P50406 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31319636 | 0.81 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL31438271 | 0.80 | REN (0.33) | IMPDH2NR3C1PGRNR3C2AR | |
| SCHEMBL31438256 | 0.80 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL31438269 | 0.80 | PRMT5 (0.33) | PRMT5WDR77 | |
| SCHEMBL31438250 | 0.79 | MET (0.38) | METIMPDH2NR3C1PGRNR3C2 | |
| SCHEMBL31438280 | 0.77 | IKBKE (0.36) | METIMPDH2ROCK2ROCK1CDC42BPB | |
| SCHEMBL31438275 | 0.75 | REN (0.34) | METIMPDH2NR3C1PGRNR3C2 | |
| SCHEMBL31438289 | 0.73 | BRD4 (0.45) | HTR2CHTR2ANR3C1PGRNR3C2 | |
| SCHEMBL26980813 | 0.71 | DYRK1A (0.49) | HTR2AARDYRK1AHTR6 | |
| SCHEMBL17850535 | 0.70 | TRIM24 (0.51) | HTR2ANR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585257-A | Novel 7-substituted indole sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-03-07 | — | — | CN | disclosed |