Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 3/20 | 0.37 |
| ▸ | CHUK | O15111 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16320756 | 0.76 | AHR (0.44) | AHRTNFRIPK1IKBKBCSNK2A1 | |
| SCHEMBL31319703 | 0.76 | CCR1 (0.46) | AHRTNFRIPK1NPC1AXL | |
| SCHEMBL31438282 | 0.75 | AHR (0.47) | AHRTNFRIPK1KEAP1AXL | |
| SCHEMBL23877944 | 0.74 | IKBKB (0.44) | AHRTNFRIPK1NPC1IKBKB | |
| SCHEMBL20426904 | 0.74 | NPC1 (0.35) | AHRTNFRIPK1NPC1IKBKB | |
| SCHEMBL30260903 | 0.71 | TNF (0.63) | AHRTNFRIPK1KEAP1CSNK2A1 | |
| SCHEMBL476686 | 0.71 | TNF (0.63) | AHRTNFRIPK1KEAP1CSNK2A1 | |
| SCHEMBL31319712 | 0.70 | AHR (0.42) | AHRTNFRIPK1AXLSLC6A2 | |
| SCHEMBL26980445 | 0.70 | POLB (0.49) | AHRTNFRIPK1CDK4CCND1 | |
| SCHEMBL31438296 | 0.69 | PTPRC (0.58) | AHRTNFRIPK1IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585257-A | Novel 7-substituted indole sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-03-07 | — | — | CN | disclosed |