Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31319703 | 0.81 | CCR1 (0.46) | AHRTNFRIPK1AXLNUDT1 | |
| SCHEMBL30741488 | 0.74 | AHR (0.43) | AHRAXLNUDT1 | |
| SCHEMBL31438282 | 0.74 | AHR (0.47) | AHRTNFRIPK1AXLNUDT1 | |
| SCHEMBL31438285 | 0.70 | AHR (0.50) | AHRTNFRIPK1SLC6A2SLC6A4 | |
| SCHEMBL30752372 | 0.70 | NOTUM (0.41) | AHRTNFRIPK1 | |
| SCHEMBL30752361 | 0.70 | AHR (0.39) | AHRTNFRIPK1 | |
| SCHEMBL31319716 | 0.70 | CCR1 (0.44) | AHRTNFRIPK1AXLGRM5 | |
| SCHEMBL31319726 | 0.70 | AHR (0.39) | AHRTNFRIPK1 | |
| SCHEMBL31319636 | 0.69 | PRMT5 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31319759 | 0.68 | CCR1 (0.49) | AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119585257-A | Novel 7-substituted indole sulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2025038863-A1 | INDOLE AND PYRROLOYPYRIDINE DERIVATIVES AS GPR17 MODULATORS | BIOGEN MA INC. (US) | 2025-02-20 | — | — | WO | disclosed |