Sugi Predict

Sugi Predict / Compounds / Bromide

Bromide

Bromide

SCHEMBL31320108

COC(=O)c1cc[n+](Cc2ccccc2)c(C2CC2)c1.[Br-]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 1/20 0.45
▸ ALDH1A1 P00352 2/20 0.43
▸ APOBEC3A P31941 1/20 0.41
▸ APOBEC3G Q9HC16 1/20 0.41
▸ LOXL2 Q9Y4K0 1/20 0.41
▸ HPGD P15428 2/20 0.40
▸ LMNA P02545 1/20 0.40
▸ CYP4F2 P78329 2/20 0.40
▸ CYP4A11 Q02928 2/20 0.40
▸ TSHR P16473 1/20 0.40
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ KDM5B Q9UGL1 1/20 0.39
▸ MGLL Q99685 1/20 0.39
▸ SLC7A5 Q01650 1/20 0.39
▸ HIF1A Q16665 1/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL31320109 0.90 KDM5B (0.46) PKMALDH1A1APOBEC3AAPOBEC3GLOXL2
SCHEMBL21990759 0.71 PKM (0.75) PKMALDH1A1LMNATSHRCA1
Bromide SCHEMBL5196843 0.71 CA1 (0.48) PKMALDH1A1APOBEC3AAPOBEC3GHPGD
Bromide SCHEMBL3722372 0.71 CYP2D6 (0.41) ALDH1A1HPGDLMNACA1CA2
SCHEMBL31587595 0.71 RAB9A (0.47) PKMALDH1A1LOXL2HPGDLMNA
SCHEMBL22637152 0.71 RAB9A (0.47) PKMALDH1A1LOXL2HPGDLMNA
Hydrochloric Acid SCHEMBL19468869 0.71 KDM4E (0.38) ALDH1A1HPGDLMNANPC1RAB9A
SCHEMBL14593147 0.70 CA1 (0.49) PKMAPOBEC3AAPOBEC3GLOXL2HPGD
SCHEMBL31430600 0.69 HPGD (0.53) PKMHPGDLMNANPC1RAB9A
SCHEMBL13153777 0.69 CYP2D6 (0.42) ALDH1A1HPGDLMNACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066329-A1 PIPERIDINYLPYRIDINYLCARBONITRILE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-02-27 — — US disclosed
WO-2025036713-A1 PIPERIDINYLPYRIDINYLCARBONITRILE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-02-20 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066329-A1 PIPERIDINYLPYRIDINYLCARBONITRILE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN QPCT, QPCTL, GLUL PKM 1652/4885ALDH1A1 3857/4885APOBEC3A 3680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.