Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.31 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31320133 | 0.85 | GRM4 (0.34) | MAPK1MAOAMAOBNPC1RAB9A | |
| SCHEMBL31320125 | 0.85 | ABL1 (0.44) | MAPK1ABL1 | |
| SCHEMBL31320117 | 0.80 | KDM4E (0.39) | MAPK1 | |
| SCHEMBL23694234 | 0.79 | MEN1 (0.38) | MAPK1 | |
| SCHEMBL31320121 | 0.74 | MAPK1 (0.38) | MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL27224623 | 0.74 | L3MBTL1 (0.36) | — | |
| SCHEMBL29425410 | 0.74 | L3MBTL1 (0.36) | — | |
| SCHEMBL31320131 | 0.73 | ABL1 (0.44) | MAPK1ABL1 | |
| SCHEMBL31320130 | 0.73 | AURKA (0.50) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31166758 | 0.72 | AAK1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240108-A1 | ARYL UREA PARP1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2024-11-28 | — | — | WO | disclosed |