Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31320131 | 0.87 | ABL1 (0.44) | ABL1MAPK1KITFGFR1SRC | |
| SCHEMBL31320119 | 0.85 | MAPK1 (0.37) | ABL1MAPK1 | |
| SCHEMBL23694234 | 0.82 | MEN1 (0.38) | MAPK1 | |
| SCHEMBL31320136 | 0.78 | GAA (0.51) | ABL1 | |
| SCHEMBL31320121 | 0.77 | MAPK1 (0.38) | MAPK1 | |
| SCHEMBL29425410 | 0.77 | L3MBTL1 (0.36) | — | |
| SCHEMBL27224623 | 0.77 | L3MBTL1 (0.36) | — | |
| SCHEMBL31320130 | 0.76 | AURKA (0.50) | — | |
| SCHEMBL31032965 | 0.75 | KDR (0.41) | ABL1FGFR1SRCPIK3CAMAPK8 | |
| SCHEMBL31166758 | 0.75 | AAK1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024240108-A1 | ARYL UREA PARP1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2024-11-28 | — | — | WO | disclosed |