Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.64 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415896 | 0.90 | LTA4H (0.60) | LTA4HALOX5OR51E2KDM4EALDH1A1 | |
| SCHEMBL3691758 | 0.88 | PPARA (0.62) | LTA4HKDM4EALDH1A1CYP2D6PPARA | |
| SCHEMBL11426661 | 0.87 | LTA4H (0.58) | LTA4HKDM4EALDH1A1CYP2D6POLB | |
| SCHEMBL15721367 | 0.87 | ALOX5 (0.58) | LTA4HALOX5OR51E2ALDH1A1PPARA | |
| SCHEMBL10820441 | 0.85 | ALOX5 (0.55) | LTA4HALOX5OR51E2ALDH1A1PPARA | |
| SCHEMBL10307841 | 0.84 | ALOX5 (0.77) | ALOX5OR51E2KDM4EALDH1A1POLB | |
| SCHEMBL5688130 | 0.84 | LTA4H (0.60) | LTA4HKDM4EALDH1A1CYP2D6PPARA | |
| SCHEMBL5958258 | 0.81 | ALDH1A1 (0.56) | LTA4HALDH1A1CYP2D6MAPTKMT2A | |
| SCHEMBL10307817 | 0.81 | ALOX5 (0.91) | LTA4HALOX5OR51E2ALDH1A1CYP2D6 | |
| SCHEMBL12018281 | 0.81 | ALOX5 (0.80) | LTA4HALOX5OR51E2CYP2D6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4483866-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF CANCER | Makrolife Biotech GmbH (DE) | 2025-01-01 | — | — | EP | claimed |
| EP-4483866-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF CANCER | Makrolife Biotech GmbH (DE) | 2025-01-01 | — | — | EP | disclosed |