Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31322202 | 1.00 | HSD11B1 (0.46) | HSD11B1OPRM1HCRTR1HCRTR2LIPE | |
| SCHEMBL31322241 | 0.88 | HSD11B1 (0.44) | HSD11B1OPRM1HCRTR1HCRTR2LIPE | |
| SCHEMBL31322214 | 0.88 | HSD11B1 (0.44) | HSD11B1OPRM1HCRTR1HCRTR2LIPE | |
| SCHEMBL31322195 | 0.88 | HSD11B1 (0.44) | HSD11B1OPRM1HCRTR1HCRTR2LIPE | |
| SCHEMBL2117117 | 0.82 | MDM2 (0.45) | HSD11B1KMT2A | |
| SCHEMBL31322239 | 0.77 | OPRM1 (0.44) | HSD11B1OPRM1ACHEKMT2AMEN1 | |
| SCHEMBL2295538 | 0.75 | KMT2A (0.46) | HSD11B1KMT2A | |
| SCHEMBL2295755 | 0.75 | KMT2A (0.46) | HSD11B1KMT2A | |
| SCHEMBL2295888 | 0.75 | KMT2A (0.46) | HSD11B1KMT2A | |
| SCHEMBL2297025 | 0.75 | KMT2A (0.46) | HSD11B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038930-A1 | AZEPANE AND PYRROLIDINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS, INC. (CA) | 2025-02-20 | — | — | WO | disclosed |