Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.37 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | BACE1 | P56817 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31322228 | 0.80 | OPRM1 (0.47) | OPRM1DRD4DRD2DRD3HSD11B1 | |
| SCHEMBL31322202 | 0.77 | HSD11B1 (0.46) | OPRM1HSD11B1ACHEMEN1KMT2A | |
| SCHEMBL31322210 | 0.77 | HSD11B1 (0.46) | OPRM1HSD11B1ACHEMEN1KMT2A | |
| SCHEMBL2602809 | 0.74 | CYP2D6 (0.54) | OPRM1DRD4DRD3LTA4HCYP2D6 | |
| SCHEMBL2605879 | 0.73 | CYP2D6 (0.49) | OPRM1DRD4LTA4HCYP2D6 | |
| SCHEMBL2115070 | 0.72 | CYP2D6 (0.47) | OPRM1DRD4LTA4HCYP2D6 | |
| SCHEMBL31322241 | 0.69 | HSD11B1 (0.44) | OPRM1HSD11B1ACHEMEN1KMT2A | |
| SCHEMBL31322214 | 0.69 | HSD11B1 (0.44) | OPRM1HSD11B1ACHEMEN1KMT2A | |
| SCHEMBL31322195 | 0.69 | HSD11B1 (0.44) | OPRM1HSD11B1ACHEMEN1KMT2A | |
| SCHEMBL2115059 | 0.69 | CYP2D6 (0.44) | OPRM1LTA4HCYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038930-A1 | AZEPANE AND PYRROLIDINE COMPOUNDS AND USES THEREOF | XENON PHARMACEUTICALS, INC. (CA) | 2025-02-20 | — | — | WO | disclosed |