Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31323947 | 0.81 | LMNA (0.64) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL1991870 | 0.79 | HDAC6 (0.63) | LMNAHDAC6HDAC1HDAC2HDAC8 | |
| SCHEMBL12485058 | 0.79 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL12485447 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL12485507 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL21999705 | 0.76 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL27679944 | 0.76 | SLC22A12 (0.50) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL12486165 | 0.75 | KDM4E (0.82) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL27693950 | 0.74 | LMNA (0.73) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL23368395 | 0.74 | RAB9A (0.52) | KDM4EALDH1A1HPGDRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119285617-A | 1,3, 5-Trisubstituted indole derivatives and use thereof | 沈阳药科大学 | 2025-01-10 | — | — | CN | disclosed |