SCHEMBL31324166

SCHEMBL31324166

COC(=O)Cc1ccc2[nH]c3ccc(Cl)cc3c2c1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
MAPT P10636 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
KDM4E B2RXH2 1/20 0.54
HPGD P15428 1/20 0.54
HSD17B10 Q99714 1/20 0.54
CNR1 P21554 4/20 0.50
SIRT1 Q96EB6 5/20 0.47
NR4A2 P43354 1/20 0.46
GAA P10253 1/20 0.46
GFER P55789 1/20 0.46
PTGS2 P35354 2/20 0.45
ABCC4 O15439 1/20 0.45
C5 P01031 1/20 0.45
PTGS1 P23219 1/20 0.45
PDE4D Q08499 1/20 0.45
ALOX5 P09917 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31324178 0.93 MAPT (0.50) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL11018311 0.93 PTGS2 (0.51) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL31324154 0.93 PTGS2 (0.51) ALDH1A1MAPTMEN1KMT2AKDM4E
Methane SCHEMBL28656788 0.92 PTGS2 (0.50) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL31324202 0.84 ALDH1A1 (0.55) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL13697649 0.84 KDM4E (0.55) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL31324183 0.83 KDM4E (0.60) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL31324221 0.83 MAPT (0.54) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL31324177 0.83 ALDH1A1 (0.54) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL31324199 0.82 MEN1 (0.81) ALDH1A1MAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743082-A1 CARBAZOLE COMPOUNDS AND THEIR USE IN THERAPY, IN THE TREATMENT OF A RESPIRATORY INFECTION UCL Business Ltd (GB) 2026-05-20 EP disclosed
WO-2025012634-A1 CARBAZOLE COMPOUNDS AND THEIR USE IN THERAPY, IN THE TREATMENT OF A RESPIRATORY INFECTION UCL BUSINESS LTD (GB) 2025-01-16 WO disclosed