Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 2/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439539 | 0.91 | ALDH1A1 (0.67) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| Methane SCHEMBL28732838 | 0.90 | ALDH1A1 (0.65) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL31324202 | 0.85 | ALDH1A1 (0.55) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL31324166 | 0.84 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL31324221 | 0.84 | MAPT (0.54) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL31324177 | 0.84 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL31324183 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL31324178 | 0.83 | MAPT (0.50) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL31324185 | 0.81 | KDM4E (0.83) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL18938363 | 0.81 | KDM4E (0.83) | KDM4EALDH1A1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743082-A1 | CARBAZOLE COMPOUNDS AND THEIR USE IN THERAPY, IN THE TREATMENT OF A RESPIRATORY INFECTION | UCL Business Ltd (GB) | 2026-05-20 | — | — | EP | disclosed |
| WO-2025012634-A1 | CARBAZOLE COMPOUNDS AND THEIR USE IN THERAPY, IN THE TREATMENT OF A RESPIRATORY INFECTION | UCL BUSINESS LTD (GB) | 2025-01-16 | — | — | WO | disclosed |
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | XINJIANG HUASHIDAN PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | TPH1, HTR1F, TPH2 | KDM4E 2869/4885ALDH1A1 324/4885MAPT 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.