Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324507 | 0.85 | MAOA (0.35) | KDM4EALDH1A1LMNA | |
| SCHEMBL31324547 | 0.81 | KDM4E (0.34) | KDM4EALDH1A1LMNA | |
| SCHEMBL31324554 | 0.78 | TACR1 (0.53) | TSHRKDM4EALDH1A1TACR1LMNA | |
| SCHEMBL31324552 | 0.78 | PDE10A (0.35) | KDM4EALDH1A1LMNA | |
| SCHEMBL22981482 | 0.77 | EPHX2 (0.38) | KDM4ETACR1 | |
| SCHEMBL31324487 | 0.74 | KDM4E (0.43) | TSHRKDM4EALDH1A1TACR1LMNA | |
| SCHEMBL31324516 | 0.73 | HSD11B1 (0.33) | TSHRKDM4EALDH1A1 | |
| SCHEMBL31324493 | 0.73 | KDM4E (0.32) | KDM4EALDH1A1LMNA | |
| SCHEMBL31324533 | 0.72 | KDM4E (0.34) | KDM4EALDH1A1TACR1LMNA | |
| SCHEMBL31324576 | 0.72 | KDM4E (0.32) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013751-B1 | 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-01-22 | — | — | EP | disclosed |