Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324487 | 0.87 | KDM4E (0.43) | TACR1KDM1AMAOAMAOBTSHR | |
| SCHEMBL22981482 | 0.83 | EPHX2 (0.38) | TACR1KDM4E | |
| SCHEMBL31324528 | 0.78 | TSHR (0.34) | TACR1TSHRLMNAALDH1A1KDM4E | |
| SCHEMBL25698598 | 0.77 | HPGD (0.39) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL24316220 | 0.76 | TACR1 (0.60) | TACR1KDM1AMAOAMAOBTSHR | |
| SCHEMBL31324516 | 0.74 | HSD11B1 (0.33) | TSHRMEN1KMT2AALDH1A1GAA | |
| SCHEMBL31324515 | 0.74 | CARM1 (0.40) | TACR1KDM1AMAOAMAOBLMNA | |
| SCHEMBL31324532 | 0.73 | KDM1A (0.51) | KDM1AKMT2ALMNA | |
| SCHEMBL9294551 | 0.72 | TACR1 (0.69) | TACR1KDM1AMAOAMAOB | |
| SCHEMBL27327207 | 0.72 | TACR1 (0.69) | TACR1KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013751-B1 | 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-01-22 | — | — | EP | disclosed |