Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.49 |
| ▸ | PI4KA | P42356 | 5/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.48 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CCNH | P51946 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324975 | 1.00 | PIK3CA (0.55) | PIK3CAPIK3CDPIK3CGPIK3CBPTGES | |
| SCHEMBL31324974 | 1.00 | PIK3CA (0.55) | PIK3CAPIK3CDPIK3CGPIK3CBPTGES | |
| SCHEMBL21091495 | 0.79 | PIK3CA (0.75) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KA | |
| SCHEMBL5766578 | 0.78 | RAB9A (0.58) | — | |
| SCHEMBL31324982 | 0.78 | MEN1 (0.54) | PIK3CAPIK3CDPIK3CGPIK3CB | |
| SCHEMBL31325002 | 0.78 | LIPC (0.53) | LIMK1FTO | |
| SCHEMBL31324993 | 0.77 | SMN1; SMN2 (0.49) | PIK3CAPIK3CDPIK3CGPIK3CBLIMK1 | |
| SCHEMBL799211 | 0.77 | PIK3CA (0.64) | PIK3CAPIK3CDPIK3CGPIK3CBPI4KA | |
| SCHEMBL31324979 | 0.76 | CYP2C9 (0.57) | — | |
| SCHEMBL31324992 | 0.76 | CYP2C9 (0.57) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504643-A | 3- (2-Aminobenzo [ d ] thiazol-5-yl) benzamide derivative and preparation method and application thereof | 贵州省天然产物研究中心 | 2025-02-25 | — | — | CN | disclosed |
| CN-119504643-A | 3- (2-Aminobenzo [ d ] thiazol-5-yl) benzamide derivative and preparation method and application thereof | 贵州省天然产物研究中心 | 2025-02-25 | — | — | CN | disclosed |