SCHEMBL31325564

SCHEMBL31325564

COCCCNC(=O)c1ccc(Cn2c(NS(=O)(=O)c3ccccc3)nc3ccccc32)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
POLB P06746 2/20 0.51
DRD2 P14416 2/20 0.49
TBXA2R P21731 2/20 0.49
NLRP3 Q96P20 3/20 0.49
RXFP1 Q9HBX9 1/20 0.49
MAPT P10636 1/20 0.48
HTT P42858 1/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC6 Q9UBN7 2/20 0.48
LMNA P02545 1/20 0.48
HPGD P15428 1/20 0.48
MAPK10 P53779 1/20 0.48
KDM4E B2RXH2 1/20 0.48
KMT2A Q03164 1/20 0.48
KCNH2 Q12809 1/20 0.47
TP53 P04637 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31325524 0.82 DRD2 (0.61) ALDH1A1POLBDRD2TBXA2RNLRP3
SCHEMBL31325536 0.82 KCNH2 (0.58) ALDH1A1POLBDRD2TBXA2RNLRP3
SCHEMBL31325545 0.80 NLRP3 (0.56) ALDH1A1POLBDRD2TBXA2RNLRP3
SCHEMBL31325566 0.78 HDAC3 (0.71) DRD2TBXA2RNLRP3RXFP1HDAC1
SCHEMBL31325537 0.77 POLB (0.51) ALDH1A1POLBNLRP3RXFP1MAPT
SCHEMBL31325506 0.75 NLRP3 (0.68) ALDH1A1POLBDRD2TBXA2RNLRP3
SCHEMBL31325561 0.74 NLRP3 (0.67) DRD2TBXA2RNLRP3RXFP1HDAC1
SCHEMBL31325542 0.74 NLRP3 (0.80) DRD2TBXA2RNLRP3MAPTHDAC1
SCHEMBL31325521 0.74 NLRP3 (0.80) DRD2TBXA2RNLRP3HDAC1HDAC6
SCHEMBL31325560 0.73 NLRP3 (0.81) DRD2TBXA2RNLRP3HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119060050-A Benzimidazole compound and application thereof 中国药科大学 2024-12-03 CN disclosed