Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 2/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396984 | 1.00 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL28861097 | 0.89 | PDGFRB (0.47) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL28433430 | 0.88 | NR1I3 (0.44) | MAPTHPGDADORA3ADORA1MEN1 | |
| SCHEMBL29927997 | 0.86 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL14904349 | 0.81 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL27991340 | 0.79 | MAPT (0.51) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL17689696 | 0.79 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL8779228 | 0.79 | L3MBTL1 (0.40) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL29593137 | 0.79 | CYP1A2 (0.63) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL4846588 | 0.79 | CYP1A2 (0.63) | NPC1RAB9ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306674-A | Preparation method of 2-phenylquinazoline-4 (3H) ketone compound | 重庆医科大学 | 2025-01-14 | — | — | CN | claimed |
| CN-119306674-A | Preparation method of 2-phenylquinazoline-4 (3H) ketone compound | 重庆医科大学 | 2025-01-14 | — | — | CN | disclosed |