SCHEMBL17689696

SCHEMBL17689696

Cc1ccc2cnc(-c3ccccc3)nc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 2/20 0.51
▸ RAB9A P51151 2/20 0.51
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ LMNA P02545 1/20 0.51
▸ MAPT P10636 1/20 0.51
▸ RECQL P46063 1/20 0.51
▸ ALDH1A1 P00352 3/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ HPGD P15428 2/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ MAOA P21397 3/20 0.48
▸ MAOB P27338 3/20 0.48
▸ ADORA3 P0DMS8 1/20 0.48
▸ ADORA2A P29274 1/20 0.48
▸ ADORA1 P30542 1/20 0.48
▸ CYP1A2 P05177 3/20 0.47
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ PSMB5 P28074 1/20 0.45
▸ POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28294779 0.89 CYP1A2 (0.47) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL17691569 0.86 MAOA (0.58) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL22244910 0.83 CYP1A2 (0.42) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL17149174 0.81 CYP1A2 (0.43) ALDH1A1KDM4EHPGDCYP1A2KMT2A
SCHEMBL8779396 0.81 KDM4E (0.47) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL27991340 0.79 MAPT (0.51) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL396984 0.79 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL31325776 0.79 NPC1 (0.51) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL24617679 0.79 NPC1 (0.47) NPC1RAB9ASMN1; SMN2LMNAMAPT
SCHEMBL31325764 0.79 NPC1 (0.59) NPC1RAB9ASMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118125985-A Method for preparing quinazolinone by activating alkylbenzene benzyl site C (sp 3) -H bond by photo-generated chlorine free radical 桂林理工大学 2024-06-04 — — CN disclosed
US-20220399506-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-15 — — US disclosed
US-20220393116-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-12-08 — — US disclosed
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 — — US disclosed
CN-109879820-A A kind of synthetic method of quinazolinone heterocyclic compound 扬州大学 2019-06-14 — — CN disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 — — US disclosed
CN-104496915-B Synthetic method of quinazolinone aromatic compound 华侨大学 2017-05-03 — — CN disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 — — US disclosed
EP-3010065-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2016-04-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220393116-A1 ELECTROLUMINESCENT DEVICE L1CAM, MCOLN2, MCOLN1 NPC1 2691/4885RAB9A 570/4885SMN1; SMN2 1434/4885
US-20220399506-A1 ELECTROLUMINESCENT DEVICE L1CAM, LDHA, LDHB NPC1 3584/4885RAB9A 1818/4885SMN1; SMN2 3344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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