Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 3/20 | 0.59 |
| ▸ | AURKA | O14965 | 4/20 | 0.58 |
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.58 |
| ▸ | GSK3A | P49840 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.55 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.55 |
| ▸ | CDC7 | O00311 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | PRKACA | P17612 | 1/20 | 0.55 |
| ▸ | CDK7 | P50613 | 1/20 | 0.55 |
| ▸ | CDK9 | P50750 | 1/20 | 0.55 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.55 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.50 |
| ▸ | SYK | P43405 | 2/20 | 0.50 |
| ▸ | IGF1R | P08069 | 2/20 | 0.50 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15487712 | 0.83 | ALOX15 (0.52) | ULK1AURKAKDRAURKBGSK3A | |
| SCHEMBL1916571 | 0.81 | GSK3A (0.56) | AURKAKDRAURKBGSK3AGSK3B | |
| SCHEMBL13166508 | 0.79 | PTK2 (0.71) | ULK1AURKAKDRAURKBGSK3A | |
| SCHEMBL20953571 | 0.78 | RAB9A (0.59) | AURKAKDRAURKBGSK3AGSK3B | |
| SCHEMBL669825 | 0.76 | ULK1 (0.61) | ULK1GSK3AGSK3BMAP4K4IRAK4 | |
| SCHEMBL28223543 | 0.76 | JAK2 (0.62) | AURKAKDRAURKBGSK3AGSK3B | |
| SCHEMBL10187855 | 0.76 | BCL6 (0.53) | AURKAKDRAURKBGSK3AGSK3B | |
| SCHEMBL17547501 | 0.76 | ULK1 (0.71) | ULK1AURKAKDRAURKBSYK | |
| SCHEMBL31725454 | 0.75 | AURKA (0.54) | ULK1AURKAKDRAURKBPTK2 | |
| SCHEMBL31725453 | 0.75 | AURKA (0.54) | ULK1AURKAKDRAURKBPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119499253-A | Application of compound in inhibiting Aurora and JAK kinase family activity and in treating several tumors | 贵州医科大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-119499253-A | Application of compound in inhibiting Aurora and JAK kinase family activity and in treating several tumors | 贵州医科大学 | 2025-02-25 | — | — | CN | disclosed |