Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL545249 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1RAB9AMAPTGAA | |
| SCHEMBL3345939 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1RAB9AMAPTGAA | |
| SCHEMBL16478033 | 0.77 | PIK3CG (0.50) | KDM4EALDH1A1RAB9AMAPTL3MBTL1 | |
| SCHEMBL20048908 | 0.76 | CSNK1A1 (0.45) | KDM4EALDH1A1RAB9AMAPTL3MBTL1 | |
| SCHEMBL21097673 | 0.76 | KDM4E (0.36) | KDM4EALDH1A1RAB9AMAPTGAA | |
| SCHEMBL23728535 | 0.75 | APOBEC3A (0.53) | KDM4EALDH1A1RAB9AMAPTGAA | |
| SCHEMBL2749583 | 0.74 | RAB9A (0.58) | KDM4EALDH1A1RAB9AMAPTGAA | |
| SCHEMBL21033151 | 0.72 | KDM4E (0.48) | KDM4EALDH1A1RAB9AMAPTGAA | |
| SCHEMBL5063124 | 0.72 | KDM4E (0.40) | KDM4EALDH1A1RAB9AMAPTL3MBTL1 | |
| SCHEMBL10591740 | 0.70 | KDM4E (0.33) | KDM4EALDH1A1L3MBTL1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100075993-A1 | SMALL MOLECULE INHIBITORS AGAINST WEST NILE VIRUS REPLICATION | DREXEL UNIVERSITY (US) | 2010-03-25 | — | — | US | disclosed |
| US-4067970-A | NEMATOCIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075993-A1 | SMALL MOLECULE INHIBITORS AGAINST WEST NILE VIRUS REPLICATION | MAVS, ZC3HAV1, KDM4E | KDM4E 3/4885ALDH1A1 4768/4885RAB9A 2522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.