Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MARS1 | P56192 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1338677 | 0.99 | SIGMAR1 (0.37) | SIGMAR1KCNH2MARS1MCHR1CYP3A4 | |
| SCHEMBL1338017 | 0.89 | GABRA1 (0.43) | MARS1SLC16A3SLC16A1MCTS1GABRA1 | |
| SCHEMBL1339707 | 0.83 | MARS1 (0.47) | SIGMAR1MARS1GABRA1GABRG2GABRB3 | |
| SCHEMBL1339551 | 0.81 | MCHR1 (0.37) | KCNH2MCHR1CYP3A4CYP2C19HTR2A | |
| SCHEMBL1339397 | 0.78 | MARS1 (0.39) | SIGMAR1MARS1GABRA1GABRG2GABRB3 | |
| SCHEMBL1338626 | 0.78 | MARS1 (0.49) | MARS1 | |
| SCHEMBL1339487 | 0.76 | MCHR1 (0.41) | MCHR1CYP3A4CYP2C19 | |
| SCHEMBL1339170 | 0.75 | MARS1 (0.38) | MARS1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL1339384 | 0.74 | GABRA1 (0.36) | SLC16A3SLC16A1MCTS1GABRA1GABRG2 | |
| SCHEMBL1337031 | 0.74 | CNR1 (0.35) | MARS1MCHR1CYP3A4CYP2C19GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940840-B1 | 6-HETEROARYLPYRIDOINDOLONE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2010-07-21 | — | — | EP | disclosed |