SCHEMBL31328282

SCHEMBL31328282

Clc1ccc2[nH]cc(C3CCNC3)c2c1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 3/20 0.56
OPRM1 P35372 1/20 0.53
OPRK1 P41145 1/20 0.53
OPRL1 P41146 1/20 0.53
HTR2C P28335 2/20 0.51
ADRB2 P07550 1/20 0.51
APP P05067 1/20 0.51
IDO1 P14902 2/20 0.49
HTR3A P46098 1/20 0.49
HTR1A P08908 1/20 0.46
GPR84 Q9NQS5 1/20 0.44
HTR2A P28223 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2783286 0.92 SLC6A4 (0.54) SLC6A4OPRM1OPRK1OPRL1HTR2C
SCHEMBL2781047 0.91 HTR2C (0.62) SLC6A4OPRM1OPRK1OPRL1HTR2C
Hydrochloric Acid SCHEMBL893002 0.90 HTR2C (0.63) SLC6A4OPRM1OPRK1OPRL1HTR2C
SCHEMBL1445394 0.82 GABRP (0.54) SLC6A4HTR2CADRB2APPIDO1
SCHEMBL5453495 0.82 SLC6A4 (0.56) SLC6A4OPRM1OPRK1OPRL1HTR2C
SCHEMBL4072108 0.82 HTR3A (0.45) SLC6A4HTR2CADRB2IDO1HTR3A
Hydrochloric Acid SCHEMBL1720653 0.81 HTR3A (0.44) SLC6A4HTR2CADRB2IDO1HTR3A
SCHEMBL18474132 0.80 SLC6A4 (0.60) SLC6A4OPRM1OPRK1OPRL1HTR2C
SCHEMBL8304104 0.80 SLC6A4 (0.64) SLC6A4IDO1HTR1AHTR2A
SCHEMBL25079811 0.79 HTR2C (0.58) SLC6A4HTR2CADRB2APPIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4729510-A1 INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF Suzhou Merna Therapeutics Co. Ltd (CN) 2026-04-22 EP disclosed
WO-2025007928-A1 INDOLE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 苏州湃芮生物科技有限公司 2025-01-09 WO disclosed