Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 3/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | NMT2 | O60551 | 1/20 | 0.51 |
| ▸ | NMT1 | P30419 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8296773 | 0.92 | NMT2 (0.53) | SLC6A4HTR2AHTR1ADRD1SLC6A2 | |
| SCHEMBL2781869 | 0.92 | SLC6A4 (0.56) | SLC6A4HTR2AHTR1ADRD1SLC6A2 | |
| SCHEMBL2781509 | 0.91 | HTR2C (0.62) | SLC6A4HTR2AHTR1ADRD1SLC6A2 | |
| SCHEMBL5097759 | 0.88 | HTR2A (0.69) | SLC6A4HTR2AHTR1AHTR2COPRM1 | |
| SCHEMBL5097763 | 0.88 | HTR2A (0.69) | SLC6A4HTR2AHTR1AHTR2COPRM1 | |
| SCHEMBL31295107 | 0.88 | HTR2A (0.69) | SLC6A4HTR2AHTR1AHTR2COPRM1 | |
| Lithium Ion SCHEMBL31530810 | 0.86 | HTR2A (0.66) | SLC6A4HTR2AHTR1AHTR2COPRM1 | |
| SCHEMBL31328282 | 0.82 | SLC6A4 (0.56) | SLC6A4HTR2AHTR1AHTR2COPRM1 | |
| SCHEMBL1445394 | 0.82 | GABRP (0.54) | SLC6A4HTR2AHTR1ADRD1SLC6A2 | |
| SCHEMBL1720378 | 0.82 | HTR2A (0.48) | SLC6A4HTR2AHTR1ADRD1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117324-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2023-04-20 | — | — | US | disclosed |
| US-20210107920-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 2021-04-15 | — | — | US | disclosed |
| US-20070225269-A1 | Use of (3-(1-(3-Phenyl-Propenyl)-Piperidin-4-Yl)-2,3-Dihydro-Indol-1-Yl)-(Pyridin-4-Yl)-Methanonone Derivatives and Related Compounds as Insecticides | SYNGENTA CROP PROTECTION, INC. | 2007-09-27 | — | — | US | disclosed |
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |
| EP-0898569-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GmbH (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997040038-A1 | PIPERIDINES AND PYRROLIDINES | MERCK PATENT GMBH (DE) | 1997-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107920-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | MGLL, LPL, LIPC | SLC6A4 4841/4885HTR2A 4035/4885HTR1A 4069/4885 |
| US-20230117324-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | MGLL, LPL, LIPC | SLC6A4 4841/4885HTR2A 4035/4885HTR1A 4069/4885 |
| US-20070225269-A1 | Use of (3-(1-(3-Phenyl-Propenyl)-Piperidin-4-Yl)-2,3-Dihydro-Indol-1-Yl)-(Pyridin-4-Yl)-Methanonone Derivatives and Related Compounds as Insecticides | CHRM1, NPY1R, MRM1 | SLC6A4 4269/4885HTR2A 2149/4885HTR1A 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.