Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | USP14 | P54578 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16720879 | 1.00 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNAMITFHTT | |
| SCHEMBL16720753 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAUSP14HPGD | |
| SCHEMBL16720857 | 0.76 | USP14 (0.50) | ALDH1A1MAPTLMNAMITFHTT | |
| SCHEMBL16720902 | 0.76 | AKR1C3 (0.48) | ALDH1A1MAPTLMNAMITFHTT | |
| SCHEMBL19538868 | 0.76 | CA12 (0.46) | ALDH1A1MAPTLMNAHPGDPOLB | |
| SCHEMBL16720694 | 0.76 | NOTUM (0.49) | ALDH1A1MAPTLMNAUSP14MAPK1 | |
| SCHEMBL31072830 | 0.76 | CA12 (0.46) | ALDH1A1MAPTLMNAHPGDPOLB | |
| SCHEMBL25712451 | 0.75 | POLB (0.51) | ALDH1A1MAPTLMNAUSP14MAPK1 | |
| SCHEMBL31329454 | 0.73 | NOTUM (0.47) | ALDH1A1MAPTLMNAUSP14MAPK1 | |
| SCHEMBL16720679 | 0.73 | NOTUM (0.47) | ALDH1A1MAPTLMNAUSP14MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585132-B | Proteasome activity enhancing compounds | 优曼尼蒂公司 | 2025-02-28 | — | — | CN | disclosed |