Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29979759 | 0.85 | ALDH1A1 (0.53) | PTGS1PTGS2MAOAMAOBPDIA6 | |
| SCHEMBL1140632 | 0.82 | CHRNB2 (0.59) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8754087 | 0.82 | CHRNB2 (0.59) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL19998971 | 0.81 | CHRNA7 (0.50) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12114958 | 0.80 | CHRNB2 (0.56) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL22269652 | 0.80 | CHRNA7 (0.51) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1260922 | 0.80 | CHRNA7 (0.61) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4906796 | 0.77 | CHRNB2 (0.60) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2937499 | 0.77 | CHRNB2 (0.60) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL21183209 | 0.77 | CHRNB2 (0.51) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250026871-A1 | CYCLIC RUTHENIUM BENZYLIDENE INITIATORS FOR ENHANCED RING EXPANSION METATHESIS POLYMERIZATION | UNIVERSITY OF WASHINGTON (US) | 2025-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250026871-A1 | CYCLIC RUTHENIUM BENZYLIDENE INITIATORS FOR ENHANCED RING EXPANSION METATHESIS POLYMERIZATION | MCM7, MCM4, MCM5 | CHRNA7 3932/4885CHRNB2 4567/4885CHRNB4 4309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.