Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 9/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8754087 | 0.84 | CHRNB2 (0.59) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1140632 | 0.84 | CHRNB2 (0.59) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12114958 | 0.83 | CHRNB2 (0.56) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3565533 | 0.83 | DRD2 (0.55) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1260922 | 0.82 | CHRNA7 (0.61) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL31329592 | 0.81 | CHRNA7 (0.48) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL20005466 | 0.80 | CHRNA7 (0.50) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL19971155 | 0.80 | CHRNB2 (0.60) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL19971166 | 0.80 | CHRNB2 (0.60) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4906796 | 0.80 | CHRNB2 (0.60) | CHRNA7CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180090687-A1 | CROSS-CONJUGATED POLYMER, MATERIAL FOR ELECTRONIC ELEMENT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT | IDEMITSU KOSAN CO., LTD (JP) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180090687-A1 | CROSS-CONJUGATED POLYMER, MATERIAL FOR ELECTRONIC ELEMENT, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, AND ORGANIC ELECTROLUMINESCENT ELEMENT | SLC18A1, SLC1A2, SLC43A1 | CHRNA7 192/4885CHRNB2 478/4885CHRNB4 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.