Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2400774 | 0.83 | HTT (0.39) | KHKHTTKMT2AGAANQO1 | |
| SCHEMBL1564745 | 0.81 | TDP1 (0.34) | KHKHTTKMT2AGAANQO1 | |
| SCHEMBL29964210 | 0.77 | HTT (0.35) | SLC9A1KHKHTTKMT2ACA1 | |
| SCHEMBL1565254 | 0.77 | KHK (0.32) | KHKHTTKMT2ACA1CA2 | |
| SCHEMBL3954054 | 0.77 | KMT2A (0.33) | KHKHTTKMT2ACA1CA2 | |
| SCHEMBL15538252 | 0.77 | LMNA (0.41) | SLC9A1HTTKMT2A | |
| SCHEMBL30413213 | 0.77 | KMT2A (0.33) | KHKHTTKMT2ACA1CA2 | |
| SCHEMBL22246500 | 0.77 | NOS3 (0.35) | KHKHTTKMT2A | |
| SCHEMBL22866631 | 0.77 | KHK (0.53) | KHKHTTKMT2ACA1CA2 | |
| SCHEMBL21246976 | 0.77 | SLC9A1 (0.38) | SLC9A1KHKKMT2AGAANQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024249817-A1 | TRICYCLIC PKMYT1 KINASE INHIBITORS | ENLIVEN INC. (US) | 2024-12-05 | — | — | WO | disclosed |