Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31386905 | 0.73 | ALDH1A1 (0.49) | BRAFALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL10714869 | 0.73 | MAPT (0.50) | ALDH1A1MAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL8421994 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13982727 | 0.71 | MAPT (0.60) | BRAFALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL29410907 | 0.70 | SLC6A3 (0.50) | BRAFALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL31386783 | 0.70 | SLC6A3 (0.41) | BRAFALDH1A1SMN1; SMN2KMT2ASLC6A3 | |
| SCHEMBL1032670 | 0.69 | ALDH1A1 (0.68) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16635495 | 0.69 | BRAF (0.47) | BRAFALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL69464 | 0.69 | SLC6A3 (0.67) | ALDH1A1MAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL9488402 | 0.69 | SLC6A3 (0.63) | BRAFALDH1A1MAPTHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371425-A | Nitrogen-containing heterocyclic compound, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2025-01-28 | — | — | CN | disclosed |