Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 18/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.56 |
| ▸ | HRH1 | P35367 | 5/20 | 0.53 |
| ▸ | HRH2 | P25021 | 4/20 | 0.53 |
| ▸ | HTR2C | P28335 | 4/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.53 |
| ▸ | HTR1E | P28566 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR2B | P41595 | 3/20 | 0.53 |
| ▸ | HTR1B | P28222 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456675 | 0.87 | TMEM97 (0.70) | TMEM97SIGMAR1HRH1HRH2HTR2C | |
| SCHEMBL31330650 | 0.85 | ALDH1A1 (0.51) | GPR119 | |
| SCHEMBL28699149 | 0.83 | TMEM97 (0.77) | TMEM97SIGMAR1HRH1HRH2HTR2C | |
| SCHEMBL30449380 | 0.83 | TMEM97 (0.77) | TMEM97SIGMAR1HRH1HRH2HTR2C | |
| SCHEMBL5727759 | 0.82 | TMEM97 (0.46) | TMEM97SIGMAR1HRH1HRH2HTR2C | |
| SCHEMBL27439728 | 0.82 | NPC1 (0.55) | NPC1RAB9AL3MBTL1TMEM97SIGMAR1 | |
| SCHEMBL30681471 | 0.79 | DRD3 (0.46) | NPC1RAB9ATMEM97SIGMAR1DRD3 | |
| SCHEMBL1842426 | 0.79 | MEN1 (0.61) | NPC1RAB9AL3MBTL1GPR119CHRM4 | |
| SCHEMBL31639586 | 0.78 | TMEM97 (0.52) | NPC1RAB9AL3MBTL1TMEM97SIGMAR1 | |
| SCHEMBL26099446 | 0.78 | TMEM97 (0.57) | NPC1RAB9AL3MBTL1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025011623-A1 | CYANOQUINOLINE-TARGETING PROTEIN DEGRADATION MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海壹迪生物技术有限公司 | 2025-01-16 | — | — | WO | disclosed |