Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 7/20 | 0.75 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.75 |
| ▸ | FLT1 | P17948 | 3/20 | 0.63 |
| ▸ | FLT4 | P35916 | 3/20 | 0.63 |
| ▸ | KDR | P35968 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5931288 | 0.93 | FLT1 (0.71) | BCL2L1MCL1FLT1FLT4KDR | |
| SCHEMBL25424924 | 0.89 | BCL2L1 (0.70) | BCL2L1MCL1FLT1FLT4KDR | |
| SCHEMBL174010 | 0.89 | FLT1 (0.77) | BCL2L1MCL1FLT1FLT4KDR | |
| SCHEMBL7278965 | 0.87 | P4HTM (0.65) | BCL2L1MCL1FLT1FLT4KDR | |
| SCHEMBL29011132 | 0.87 | FLT1 (0.74) | BCL2L1MCL1FLT1FLT4KDR | |
| Potassium SCHEMBL30358590 | 0.87 | FLT1 (0.74) | BCL2L1MCL1FLT1FLT4KDR | |
| SCHEMBL15679406 | 0.84 | FLT1 (0.61) | BCL2L1MCL1FLT1FLT4KDR | |
| SCHEMBL12489988 | 0.84 | MEN1 (0.66) | BCL2L1MCL1FLT1FLT4KDR | |
| SCHEMBL8660071 | 0.84 | MEN1 (0.87) | BCL2L1MCL1FLT1FLT4KDR | |
| SCHEMBL8825440 | 0.84 | FLT1 (0.61) | BCL2L1MCL1FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192174-A | Novel biphenyl carboxylic FXR agonist, preparation method thereof and application thereof as medicine | 广东药科大学 | 2024-12-27 | — | — | CN | claimed |
| CN-119192174-A | Novel biphenyl carboxylic FXR agonist, preparation method thereof and application thereof as medicine | 广东药科大学 | 2024-12-27 | — | — | CN | disclosed |