Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 2/20 | 0.61 |
| ▸ | FLT4 | P35916 | 2/20 | 0.61 |
| ▸ | KDR | P35968 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5931288 | 0.91 | FLT1 (0.71) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL174010 | 0.87 | FLT1 (0.77) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL7278965 | 0.86 | P4HTM (0.65) | FLT1FLT4KDRMEN1KMT2A | |
| Potassium SCHEMBL30358590 | 0.85 | FLT1 (0.74) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL29011132 | 0.85 | FLT1 (0.74) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL31331608 | 0.84 | BCL2L1 (0.75) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL24347999 | 0.83 | PTGS2 (0.67) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL8660071 | 0.83 | MEN1 (0.87) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL12489988 | 0.83 | MEN1 (0.66) | FLT1FLT4KDRMEN1KMT2A | |
| SCHEMBL15679406 | 0.83 | FLT1 (0.61) | FLT1FLT4KDRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624943-A | Pyridine compounds which are useful as leukotriene-B4 -antagonists | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |