Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 4/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331799 | 0.97 | CCR6 (0.41) | CDK5CDK5R1CCR6PIK3CAPRKDC | |
| SCHEMBL31332132 | 0.87 | CDK5 (0.40) | CDK5CDK5R1CNR1CNR2 | |
| SCHEMBL29438872 | 0.86 | CCR6 (0.43) | CDK5CDK5R1CCR6PIK3CAHCRTR1 | |
| SCHEMBL22718316 | 0.86 | CCR6 (0.43) | CDK5CDK5R1CCR6PIK3CAHCRTR1 | |
| SCHEMBL31331877 | 0.85 | CDK5 (0.39) | CDK5CDK5R1CCR6LIPEKDM4E | |
| SCHEMBL31331781 | 0.84 | LIPE (0.41) | CDK5CDK5R1CCR6LIPEKDM4E | |
| SCHEMBL22718447 | 0.83 | CCR6 (0.44) | CDK5CDK5R1CCR6HCRTR2KDM4E | |
| SCHEMBL31331820 | 0.81 | TNNI3K (0.46) | PIK3CAPRKDCHCRTR1HCRTR2KDM4E | |
| SCHEMBL24496211 | 0.78 | CCR6 (0.41) | CDK5CDK5R1CCR6KDM4EMEN1 | |
| SCHEMBL29648363 | 0.78 | CCR6 (0.41) | CDK5CDK5R1CCR6KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954725-A | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114466839-B | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-01-07 | — | — | CN | disclosed |