Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 2/20 | 0.34 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331877 | 0.86 | CDK5 (0.39) | LIPECDK5CDK5R1MMP1MMP9 | |
| SCHEMBL22718153 | 0.86 | MMP1 (0.40) | LIPECDK5CDK5R1MMP1MMP9 | |
| SCHEMBL31331799 | 0.85 | CCR6 (0.41) | LIPECDK5CDK5R1KDM4EMEN1 | |
| SCHEMBL31331755 | 0.84 | CDK5 (0.41) | LIPECDK5CDK5R1MMP1MMP9 | |
| SCHEMBL31332175 | 0.82 | TNNI3K (0.47) | LIPEKDM4EMEN1MAPTKMT2A | |
| SCHEMBL22718290 | 0.78 | CCR6 (0.37) | LIPEMMP1MMP9MMP13KDM4E | |
| SCHEMBL29438945 | 0.78 | CCR6 (0.37) | LIPEMMP1MMP9MMP13KDM4E | |
| SCHEMBL30114634 | 0.76 | BMP1 (0.50) | LIPEMMP1MMP9MMP13KDM4E | |
| SCHEMBL24496050 | 0.75 | TEAD1 (0.39) | LIPEMMP1MMP9MMP13KDM4E | |
| SCHEMBL31332132 | 0.75 | CDK5 (0.40) | CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954725-A | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114466839-B | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-01-07 | — | — | CN | disclosed |