Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30644299 | 0.89 | PTGS1 (0.52) | PTGS1GSTK1ACEOPRD1OPRM1 | |
| SCHEMBL29815598 | 0.88 | PTGS1 (0.49) | PTGS1GSTK1ACEOPRD1OPRM1 | |
| SCHEMBL30471792 | 0.87 | OPRD1 (0.52) | OPRD1OPRM1OPRK1MMEMAPT | |
| SCHEMBL31461857 | 0.87 | PTGS1 (0.45) | PTGS1GSTK1OPRD1OPRM1OPRK1 | |
| SCHEMBL29746739 | 0.86 | ACE (0.45) | PTGS1GSTK1ACEOPRD1OPRM1 | |
| SCHEMBL29387981 | 0.86 | PTGS1 (0.47) | PTGS1GSTK1ACEOPRD1OPRM1 | |
| SCHEMBL30392483 | 0.84 | MME (0.44) | PTGS1GSTK1ACEOPRD1OPRM1 | |
| SCHEMBL29939666 | 0.82 | ACE (0.50) | ACEMMEMAPTKDM4ETHRB | |
| SCHEMBL30905702 | 0.81 | PTGS1 (0.64) | PTGS1GSTK1ACEOPRD1OPRM1 | |
| SCHEMBL29700057 | 0.81 | MME (0.54) | OPRD1OPRM1OPRK1MMEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119529033-A | Ultra-long-acting polypeptide for NPR-B targeting and application thereof in skeletal system diseases | 中山大学 | 2025-02-28 | — | — | CN | disclosed |
| CN-119529033-A | Ultra-long-acting polypeptide for NPR-B targeting and application thereof in skeletal system diseases | 中山大学 | 2025-02-28 | — | — | CN | disclosed |