Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | FNTA | P49354 | 2/20 | 0.42 |
| ▸ | FNTB | P49356 | 2/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29387981 | 0.97 | PTGS1 (0.47) | PTGS1GSTK1ACEMAPTKDM4E | |
| SCHEMBL7553789 | 0.90 | MAPT (0.53) | MAPTSLC7A5OPRD1OPRM1OPRK1 | |
| SCHEMBL7150981 | 0.90 | MAPT (0.53) | MAPTSLC7A5OPRD1OPRM1OPRK1 | |
| SCHEMBL8727805 | 0.89 | PTGS1 (0.43) | PTGS1GSTK1SLC7A5OPRD1OPRM1 | |
| SCHEMBL31332455 | 0.88 | PTGS1 (0.47) | PTGS1GSTK1ACEMAPTKDM4E | |
| SCHEMBL29700057 | 0.87 | MME (0.54) | MAPTSLC7A5OPRD1OPRM1OPRK1 | |
| SCHEMBL30661448 | 0.87 | OPRD1 (0.53) | MAPTSLC7A5OPRD1OPRM1OPRK1 | |
| SCHEMBL30661446 | 0.87 | OPRD1 (0.53) | MAPTSLC7A5OPRD1OPRM1OPRK1 | |
| SCHEMBL1493227 | 0.86 | PTGS1 (0.55) | PTGS1GSTK1ACEMAPTKDM4E | |
| SCHEMBL29544382 | 0.86 | MME (0.44) | PTGS1GSTK1MAPTSLC7A5OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124552-A1 | METHODS AND COMPOSITIONS FOR GENERATING AN IMMUNE RESPONSE BY INDUCING CD40 AND PATTERN RECOGNITION RECEPTOR ADAPTERS | BAYLOR COLLEGE OF MEDICINE | 2024-04-18 | — | — | US | disclosed |
| CN-113373128-B | Epoxide hydrolase mutant with improved catalytic efficiency and preparation method thereof | 深圳市微滴科技顾问有限公司 | 2022-09-16 | — | — | CN | disclosed |