Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080398 | 0.87 | PNMT (0.48) | PNMTGABBR2GABBR1ACP3AOC3 | |
| SCHEMBL31332659 | 0.85 | PNMT (0.44) | PNMTGABBR2GABBR1ACP3AOC3 | |
| SCHEMBL31332655 | 0.85 | PNMT (0.44) | PNMTGABBR2GABBR1ACP3AOC3 | |
| SCHEMBL26947352 | 0.84 | AOC3 (0.44) | PNMTGABBR2GABBR1ACP3AOC3 | |
| SCHEMBL2628025 | 0.81 | SLC6A2 (0.43) | AOC3TAAR1IDO1TDO2 | |
| SCHEMBL7669749 | 0.79 | GABBR2 (0.58) | GABBR2GABBR1AOC3MEN1KMT2A | |
| SCHEMBL27726315 | 0.79 | GABBR2 (0.42) | PNMTGABBR2GABBR1ACP3AOC3 | |
| SCHEMBL2628024 | 0.79 | GABBR2 (0.57) | GABBR2GABBR1TAAR1LMNANPSR1 | |
| SCHEMBL4675885 | 0.79 | SLC6A2 (0.43) | PNMTGABBR2GABBR1MEN1KMT2A | |
| SCHEMBL3912571 | 0.79 | SLC6A2 (0.43) | PNMTGABBR2GABBR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |