Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.39 |
| ▸ | CHRNG | P07510 | 4/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.39 |
| ▸ | CHRND | Q07001 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755205 | 0.88 | OPRD1 (0.43) | CCR2SLC6A4SLC6A2SLC6A3CHRNA1 | |
| SCHEMBL20684979 | 0.85 | SLC6A3 (0.45) | CCR2SLC6A4SLC6A2SLC6A3CHRNA1 | |
| SCHEMBL5756820 | 0.84 | SLC6A4 (0.39) | CCR2SLC6A4SLC6A2SLC6A3CHRNA1 | |
| SCHEMBL5790394 | 0.83 | SLC6A3 (0.40) | CCR2SLC6A4SLC6A2SLC6A3CHRNA1 | |
| SCHEMBL30174859 | 0.79 | OPRM1 (0.46) | CCR2SLC6A4SLC6A2SLC6A3OPRM1 | |
| SCHEMBL25518334 | 0.79 | OPRM1 (0.46) | CCR2SLC6A4SLC6A2SLC6A3OPRM1 | |
| SCHEMBL25094761 | 0.79 | HDAC4 (0.41) | SLC6A4SLC6A2SLC6A3OPRM1OPRD1 | |
| SCHEMBL30174956 | 0.78 | SLC6A4 (0.40) | CCR2SLC6A4SLC6A2SLC6A3CHRNA1 | |
| SCHEMBL25518294 | 0.78 | SLC6A4 (0.40) | CCR2SLC6A4SLC6A2SLC6A3CHRNA1 | |
| SCHEMBL7705762 | 0.77 | SLC6A4 (0.55) | CCR2SLC6A4SLC6A2SLC6A3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709708-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ANGELINI PHARMA S.P.A. (IT) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233603-A1 | NOVEL CARBOXAMIDE DERIVATIVES | ICAGEN, LLC (US) | 2024-11-14 | — | — | WO | disclosed |