⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332884 | 1.00 | — | — | |
| SCHEMBL31332983 | 0.76 | — | — | |
| SCHEMBL31332900 | 0.76 | — | — | |
| SCHEMBL31333018 | 0.71 | CYP1A2 (0.32) | — | |
| SCHEMBL31333010 | 0.71 | — | — | |
| SCHEMBL19059638 | 0.70 | — | — | |
| SCHEMBL31332969 | 0.70 | — | — | |
| SCHEMBL31332909 | 0.69 | ADORA2B (0.33) | — | |
| SCHEMBL31332993 | 0.69 | GABRB3 (0.35) | — | |
| SCHEMBL31332913 | 0.69 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709374-A2 | KCC2 POTENTIATORS AND USES THEREOF | Axonis Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| US-20260062402-A1 | KCC2 POTENTIATORS AND USES THEREOF | AXONIS THERAPEUTICS INC (US) | 2026-03-05 | — | — | US | disclosed |
| WO-2024233885-A2 | KCC2 POTENTIATORS AND USES THEREOF | AXONIS THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |