Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272935 | 0.81 | PDE4D (0.50) | CYP1A2CYP2C9CYP2C19PDE4DALDH1A1 | |
| SCHEMBL5648877 | 0.80 | KDM4E (0.46) | CYP1A2CYP2C9CYP2C19PDE4DALDH1A1 | |
| SCHEMBL3958675 | 0.79 | KDM4C (0.43) | CYP1A2ALDH1A1KDM4EHPGDALPL | |
| SCHEMBL22815646 | 0.79 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19PDE4DALDH1A1 | |
| SCHEMBL26922505 | 0.77 | KDM4E (0.55) | CYP1A2CYP2C9CYP2C19PDE4DALDH1A1 | |
| SCHEMBL1928112 | 0.76 | PDE4D (0.44) | CYP1A2PDE4DALDH1A1KDM4EHTT | |
| SCHEMBL19780726 | 0.75 | KDM4E (0.43) | CYP1A2CYP2C9CYP2C19PDE4DALDH1A1 | |
| SCHEMBL23294640 | 0.75 | ALPL (0.55) | ALDH1A1KDM4EALPLCDC25BKMT2A | |
| SCHEMBL5648880 | 0.74 | KDM4E (0.47) | CYP1A2CYP2C9CYP2C19PDE4DALDH1A1 | |
| SCHEMBL23484645 | 0.73 | CYP1A2 (0.40) | CYP1A2CYP2C9CYP2C19PDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709374-A2 | KCC2 POTENTIATORS AND USES THEREOF | Axonis Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| US-20260062402-A1 | KCC2 POTENTIATORS AND USES THEREOF | AXONIS THERAPEUTICS INC (US) | 2026-03-05 | — | — | US | disclosed |
| WO-2024233885-A2 | KCC2 POTENTIATORS AND USES THEREOF | AXONIS THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062402-A1 | KCC2 POTENTIATORS AND USES THEREOF | HCN2, HCN1, HCN4 | CYP1A2 1523/4885CYP2C9 813/4885CYP2C19 1384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.