Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31332908 | 0.79 | CYP1A2 (0.44) | ALPLALDH1A1HSD17B10POLBKMT2A | |
| SCHEMBL1930167 | 0.78 | KDM4C (0.53) | KDM4CMAPK1MAPTNPSR1ALPL | |
| SCHEMBL9587880 | 0.78 | KDM4C (0.44) | KDM4CMAPK1MAPTNPSR1ALPL | |
| SCHEMBL9642740 | 0.76 | KDM4C (0.43) | KDM4CMAPK1MAPTNPSR1ALPL | |
| SCHEMBL21621367 | 0.76 | PDK2 (0.42) | MAPTKMT2ANPC1SMN1; SMN2KDM4E | |
| SCHEMBL23294432 | 0.76 | KDM4C (0.43) | KDM4CMAPK1MAPTNPSR1ALPL | |
| SCHEMBL2385273 | 0.74 | KDM4C (0.46) | KDM4CMAPK1NPSR1TSHRALDH1A1 | |
| SCHEMBL23939800 | 0.74 | — | — | |
| SCHEMBL7425496 | 0.73 | KDM4C (0.41) | KDM4CMAPK1MAPTNPSR1ALPL | |
| SCHEMBL19661284 | 0.71 | KDM4C (0.46) | KDM4CMAPK1MAPTNPSR1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | SIRONAX LTD (KY) | 2026-03-19 | — | — | US | disclosed |
| EP-4590674-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2025-07-30 | — | — | EP | disclosed |
| US-11008416-B2 | Aqueous, curable composition, comprising dispersed uretdione prepolymer, reactant and azolate | COVESTRO LLC (US) | 2021-05-18 | — | — | US | disclosed |
| US-20210017322-A1 | URETDIONE-CONTAINING POLYURETHANE-DISPERSIONS COMPRISING HYDROPHILIC GROUPS | COVESTRO DEUTSCHLAND AG (DE) | 2021-01-21 | — | — | US | disclosed |
| CN-111886271-A | Aqueous curable compositions comprising dispersed uretdione prepolymers, reactants, and azoles | 科思创有限公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-111868131-A | Uretdione-containing polyurethane dispersions containing hydrophilic groups | 科思创德国股份有限公司 | 2020-10-30 | — | — | CN | disclosed |
| US-20190292299-A1 | AQUEOUS, CURABLE COMPOSITION, COMPRISING DISPERSED URETDIONE PREPOLYMER, REACTANT AND AZOLATE | COVESTRO LLC | 2019-09-26 | — | — | US | disclosed |
| EP-3543269-A1 | URETDIONE-CONTAINING POLYURETHANE-DISPERSIONS COMPRISING HYDROPHILIC GROUPS | Covestro Deutschland AG (DE) | 2019-09-25 | — | — | EP | disclosed |
| EP-1937682-B1 | MET KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-1389221-B1 | METHOD FOR PRODUCING ALIPHATIC POLYISOCYANATES HAVING AN URETDIONE, ISOCYANURATE AND IMINOOXADIAZINDIONE STRUCTURE | BAYER MATERIALSCIENCE AG (DE) | 2009-07-22 | — | — | EP | disclosed |
| US-20070078140-A1 | MET kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2007-04-05 | — | — | US | disclosed |
| US-20070078140-A1 | MET kinase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2007-04-05 | — | — | US | disclosed |
| US-7030266-B2 | Method for producing polyisocyanates | BAYER AKTIENGESELLSCHAFT (DE) | 2006-04-18 | — | — | US | disclosed |
| EP-1389221-A1 | METHOD FOR PRODUCING ALIPHATIC POLYISOCYANATES HAVING AN URETDIONE, ISOCYANURATE AND IMINOOXADIAZINDIONE STRUCTURE | Bayer Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |
| EP-1389223-A1 | METHOD FOR PRODUCING POLYISOCYANATES | Bayer Aktiengesellschaft (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-6590098-B2 | Reacting isocyanates-2+ such as hexamethylene diisocyanate in the presence of catalysts, to form dimers, trimers and/or adducts used as polyurethane paints and coatings | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-08 | — | — | US | disclosed |
| US-20030078361-A1 | Method of preparing aliphatic polyisocyanates with uretdione, isocyanurate and iminooxadiazindione structures | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-24 | — | — | US | disclosed |
| US-20030078450-A1 | Method for producing polyisocyanates | COVESTRO DEUTSCHLAND AG (DE) | 2003-04-24 | — | — | US | disclosed |
| WO-2002092658-A1 | METHOD FOR PRODUCING POLYISOCYANATES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | WO | disclosed |
| WO-2002092656-A1 | METHOD FOR PRODUCING ALIPHATIC POLYISOCYANATES HAVING AN URETDIONE, ISOCYANURATE AND IMINOOXADIAZINDIONE STRUCTURE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078130-A1 | NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF | NAMPT, NNMT, SARM1 | KDM4C 3237/4885MAPK1 1908/4885MAPT 523/4885 |
| US-20030078450-A1 | Method for producing polyisocyanates | HDHD5, NISCH, DOHH | KDM4C 704/4885MAPK1 3560/4885MAPT 3422/4885 |
| US-20070078140-A1 | MET kinase inhibitors | MET, ABL1, ERBB2 | KDM4C 1016/4885MAPK1 227/4885MAPT 3276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.