Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988810 | 0.92 | ADORA2A (0.51) | ADRA1DCNOT7TSHRADORA2AMEN1 | |
| SCHEMBL5483136 | 0.82 | PKM (0.59) | ADRA1DTSHRLMNAADORA2AGAA | |
| SCHEMBL7973752 | 0.82 | SMN1; SMN2 (0.47) | TSHRLMNAMAPK1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7987445 | 0.81 | PKM (0.57) | ADRA1DTSHRLMNAADORA2AGAA | |
| SCHEMBL7984506 | 0.79 | EHMT2 (0.43) | ADRA1DCNOT7TSHRADORA2AGAA | |
| SCHEMBL7974138 | 0.78 | KMT2A (0.52) | ADRA1DCNOT7TSHRLMNAMAPK1 | |
| SCHEMBL7974495 | 0.78 | ADORA2A (0.48) | LMNAPOLBADORA2AMEN1KMT2A | |
| SCHEMBL7988146 | 0.78 | GAA (0.51) | CNOT7TSHRLMNAMAPK1MEN1 | |
| SCHEMBL31333072 | 0.77 | ADRA1D (0.48) | ADRA1DCNOT7TSHRLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL7984737 | 0.77 | ADORA2A (0.47) | LMNAPOLBADORA2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |