Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | CCND3 | P30281 | 2/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 5/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31334770 | 0.88 | MAPK8 (0.44) | MAPK1DYRK2MCHR1 | |
| SCHEMBL31333803 | 0.85 | MAPK1 (0.42) | MAPK1DYRK2CDK4CCND1CCND3 | |
| SCHEMBL31334019 | 0.85 | MAPK1 (0.38) | MAPK1DYRK2MCHR1CDK6 | |
| SCHEMBL31334086 | 0.84 | MAPK1 (0.47) | MAPK1DYRK2CKS1BSKP1SKP2 | |
| SCHEMBL31333985 | 0.84 | ADORA2A (0.38) | MAPK1DYRK2MCHR1SYK | |
| SCHEMBL31333789 | 0.83 | DYRK2 (0.38) | MAPK1DYRK2SYK | |
| SCHEMBL31334640 | 0.83 | DYRK2 (0.38) | MAPK1DYRK2SYK | |
| SCHEMBL31334289 | 0.82 | CDK9 (0.43) | MAPK1CDK4CCND1CCND3CDK6 | |
| SCHEMBL31334347 | 0.81 | DYRK2 (0.47) | MAPK1DYRK2CDK4CCND1CCND3 | |
| SCHEMBL31333206 | 0.81 | CKS1B (0.51) | MAPK1DYRK2CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709720-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | Larkspur Biosciences, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233846-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES, INC. (US) | 2024-11-14 | — | — | WO | disclosed |